Introduction

Nearly 25% of all cervical cancers are diagnosed in women under 40 years of age (1). Radical trachelectomy by vaginal approach was the first technique to be successfully used (2). Several different procedures have since been described as fertility-sparing surgery techniques (3).

A 38 years-old nulliparous woman with high grade, keratinized, squamous cell carcinoma of the cervix was referred to our clinic. She had undergone a loop electrosurgical excision procedure at another center. The pathological review and clinical examination revealed a FIGO stage IB1 cervical carcinoma without lymphovascular space invasion and less than 2 cm in the greatest diameter. Abdomino-pelvic magnetic resonance imaging showed no residual disease after loop electrosurgical excision procedure. She underwent vaginal-assisted laparoscopic surgery. One 25 mg/vial kit of indocyanine green was reconstituted in 10 mL of aqueous solvent, and then a 2 mL aliquot was further diluted in 2 mL of aqueous solvent. Four mL of indocyanine green was injected into the uterine cervix at the 3 and 9 o’clock positions, submucosally and deep of the cervix to locate the sentinel lymph nodes. In the first step, the round ligaments were coagulated, cut and dissected from the anterior and posterior leaves of the broad ligament. The ureters were identified alongside the posterior leaf of the broad ligament. The uterine arteries were then ligated bilaterally at their origin from the hypogastric artery. Both paravesical and pararectal spaces were opened to gain access to the parametria. The anterior part of the vesicouterine ligament was dissected, and the ureteral tunnel was developed. Colpotomy was performed. All procedures were performed with meticulous dissection of pelvic anatomical structures including hypogastric nerves (Video 1) (Figure 1, 2). Resection of the cervix was performed during the vaginal part of the procedure. Frozen-section examination was performed to ensure negative surgical margins. Finally, the vaginal mucosa was sutured to the stroma of the cervix. She was discharged on postoperative day four without any adverse event in the postoperative period. She had no residual tumor on final pathology. There was no metastasis on examination of the lymph nodes.

Vaginal-assisted laparoscopic nerve-sparing radical trachelectomy as a fertility-sparing procedure appears to be a safe and adequate surgical technique in selected young women with early stage cervical cancer.

Video 1.

https://www.doi.org/10.4274/jtgga.galenos.2019.2019.0121.video1

Conflict of Interest: No conflict of interest was declared by the authors.

Financial Disclosure: The authors declared that this study received no financial support.