Platelet profile in patients with gestational diabetes: a retrospective study
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Original Investigation
VOLUME: 13 ISSUE: 4
P: 223 - 226
December 2012

Platelet profile in patients with gestational diabetes: a retrospective study

J Turk Ger Gynecol Assoc 2012;13(4):223-226
1. Department Of Gynecology And Obstetrics, Faculty Of Medicine, Dicle University, Diyarbakir, Turkey
2. Department Of Obstetrics And Gynecology, Faculty Of Medicine, Dicle University, Diyarbakir, Turkey
3. Department Of Obstetrics And Gynecology, School Of Medicine, Dicle University, Diyarbakir, Turkey
4. Diyarbakir Maternity And Children Hospital, Department Of Obstetrics And Gynecology, Diyarbakir, Turkey
No information available.
No information available
Received Date: 26.07.2012
Accepted Date: 04.10.2012
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ABSTRACT

Objective:

To assess and compare alterations in the morphology and function of platelets occurring in gestational diabetes and healthy pregnancies.

Material and Methods:

A retrospective study was performed of 77 pregnant women: 42 cases with gestational diabetes and 35 healthy controls. The two groups were compared in terms of demographics and platelet parameters derived from complete blood counts.

Results:

The mean platelet volume (p=0.001) and HbA1c (p<0.001) were significantly increased in the patients with gestational diabetes. The mean platelet volume was well correlated with the platelet distribution width (rs=0.404, p<0.001) and the platelet count (rs=0.355, p=0.002)

Conclusion:

The mean platelet volume and other platelet parameters may significantly aid the identification of diabetic pregnants at risk for vascular complications. The role and possible clinical relevance of these changes during diabetic pregnancy need to be investigated in further studies.

Keywords:
Pregnancy, diabetes, gestational diabetes, platelet, mean platelet volume